This is a loss of brain function that affects memory, thinking and behavior. It is the most common form of dementia, is incurable and tends to affect people over 65 years of age.
Although the exact cause is unknown, certain genes linked to this disease have been described.
Onset may be marked by episodes of forgetfulness due to recent memory impairment. Other symptoms may also manifest, such as difficulty performing tasks that used to be simple, difficulty resolving problems, mood or personality changes that may be confused with depression, altered sleep patterns and inability to remember people, places and events. Very advanced cases are characterised by problems carrying out basic activities of daily living, such as eating, dressing and bathing, understanding language, etc.
Diagnosis is clinical, through a questioning, a physical examination and mental state evaluation tests. Additional investigations may also be performed to exclude other possible causes of dementia.
There is no cure for dementia caused by Alzheimer’s disease. However, there are therapies and medication treatments that may delay its symptom progression.
- C. Dirk Keene. Epidemiology, pathology, and pathogenesis of Alzheimer disease. UpToDate. Febrero 2016
- David A Wolk. Clinical features and diagnosis of Alzheimer disease. UpToDate. Septiembre 2016
- Daniel Press. Treatment of dementia. UpToDate. Junio 2016
- William W. Seeley. Enfermedad de Alzheimer y otras demencias. Harrison. Principios de Medicina Interna, 19e. Capítulo 448
- R. Blesa González. Enfermedad de Alzheimer y otras demencias degenerativas. Farreras Rozman. Medicina Interna, ed 18. Capítulo 175

