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It is a swelling of the parts deep in the skin and the mucous membranes, which is sometimes associated with hives as a result of an allergy (due to contact with a substance) or due to the deficiency of an enzyme (inherited cause). This swelling appears very quickly in the eyes, mouth or tongue in mild cases. If it affects the respiratory mucosa, it can cause stridor when breathing (similar to asthma attacks), causing severe respiratory failure. You must consult your doctor urgently to diagnose the problem and start treatment immediately.
- Bruce Zuraw, MD. Clifton O Bingham, III, MD. An overview of angioedema: Pathogenesis and causes. UpToDate. Sep 26, 2016.
- Bruce Zuraw, MD. Clifton O Bingham, III, MD. An overview of angioedema: Clinical features, diagnosis, and management. UpToDate. Jul 21, 2015.
- Ertoy Karagol HI, Yilmaz O, Bakirtas A, et al. Angioedema without urticaria in childhood. Pediatr Allergy Immunol 2013; 24:685.
- Ricketti AJ, Cleri DJ, Ramos-Bonner LS, Vernaleo JR. Hereditary angioedema presenting in late middle age after angiotensin-converting enzyme inhibitor treatment. Ann Allergy Asthma Immunol 2007; 98:397.
- Gallart T. Enfermedades alérgicas mediadas por anticuerpos IgE (hipersensibilidad inmediata o alergia atópica). Farreras Rozman. Medicina Interna. Volumen 2. 12º edición: 2709.
Dr. Sara Vitoria
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