Anisakis poisoning (Pediatrics - PEDS)

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Anisakiasis (or Anisakis poisoning) is the disease caused by the infection of Anisakis, a genus of parasitic nematodes whose life cycle affects fish and marine mammals, where it can cause lesions in the digestive tract.

People are accidental guests of this parasite. Larvae may be acquired if raw, uncooked or not previously frozen fish is consumed.

Gastric manifestations include abdominal pain, accompanied or not by nausea, vomiting and diarrhea, which may resemble other diseases such as appendicitis, ileitis (inflammation of the small intestine called the ileum), gastric ulcer, intestinal obstruction and even abdominal tumors. Cases, where joints and other organs (lung, liver, pancreas and spleen) were involved, have also been found.

The diagnosis is reached through medical questioning and detailed physical examination. Endoscopic procedures (e.g. gastroscopy or colonoscopy) make seeing and extracting the larvae possible.

Symptomatic treatment is enough to end this infection, as it usually ends up healing on its own over time. The best treatment for intestinal anisakiasis infection is the removal of the parasite early through a gastroscopy. Some patients require removal of the worm by means of urgent surgery. For the treatment of allergic symptoms, antihistamines, corticosteroids are usually recommended, and even adrenaline in cases with very severe symptoms.

Bibliographic references
  1. Scott H Sicherer, MD, FAAAAI. Seafood allergies: Fish and shellfish. Uptodate. May 31, 2017.
  2. Sicherer SH, Sampson HA. Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. J Allergy Clin Immunol 2014; 133:291.
  3. Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics 2011; 128:e9..
  4. Feng C, Teuber S, Gershwin ME. Histamine (Scombroid) Fish Poisoning: a Comprehensive Review. Clin Rev Allergy Immunol 2016; 50:64.
  5. Banks TA, Gada SM. Cross-reactivity and masqueraders in seafood reactions. Allergy Asthma Proc 2013; 34:497.
Author
Dr. Elvira Moreno
Copyright
© TeckelMedical 2026

Symptoms

    Skin rash


    Welts / wheals on the skin


    Itchy skin


    Swelling of mucous membrane


    Swelling

Symptoms to watch out for

Fever (temperature higher than 100.4 ºF)
Inability to evacuate the bowel or pass gas
Severe abdominal pain, which does not allow you to perform activities of daily living
Vomit with feces
History of immunodeficiency (HIV, Diabetes Mellitus, oncological disorders, long-term corticosteroid consumption).

Self-care

Take antihistamines for itching.
Cook seafood to a temperature of 145 ºF.
Freeze fish at -35ºC / -31ºF or below until solid and store at the same temperature for 15 hours.