Caffeine poisoning

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Caffeine is a stimulant that works mainly on the Central Nervous System (brain).

The most common cause of poisoning is accidental ingestion of an amount that is greater than the recommended one or as an intentional means of self-harm (together with other substances).

It causes agitation, nervousness, insomnia, incoherent flow of thoughts and words, increase in urination, stomach pain, nausea and vomiting, muscle twitching, palpitations and sweating. It may produce life-threatening symptoms such as cardiac arrhythmia or seizures.

Diagnosis is reached through the collection of clinical history and physical examination.

In mild cases, treatment consists of managing symptoms. Vital signs, such as temperature, pulse, breathing rate, and blood pressure will be monitored. In severe poisonings, it will be necessary to ensure general support measures in a hospital. In early stages, pumping the stomach and administering activated carbon may be considered.

Bibliographic references
  1. Bryan Bordeaux, Harris R Lieberman. Benefits and risks of caffeine and caffeinated beverages. UpToDate. Jun 29, 2016.
  2. Elsa-Grace Giardina. Cardiovascular effects of caffeine and caffeinated beverages. UpToDate. Jul 30, 2015.
  3. Frost L, Vestergaard P. Caffeine and risk of atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study. Am J Clin Nutr 2005; 81:578.
  4. Ding M, Bhupathiraju SN, Satija A, et al. Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies. Circulation 2014; 129:643.
  5. Liu J, Sui X, Lavie CJ, et al. Association of coffee consumption with all-cause and cardiovascular disease mortality. Mayo Clin Proc 2013; 88:1066.
  6. Indalecio Morán, Jaume Baldirà, Luís Marruecos, Santiago Nogué. Intoxicación aguda por bebidas energizantes (A base de taurina, inositol y cafeína). Intoxicación clínica. Capítulo 45. Páginas 535-539. Grupo Difusión
Author
Dr. Sara Vitoria
Copyright
© TeckelMedical 2026

Symptoms

    Change in mood and/or behavior


    Difficulty sleeping


    State of anxiety


    Difficulty relaxing


    Passing large amounts of urine

Symptoms to watch out for

If it is accompanied by seizures
Reduction in the level of consciousness
Difficulty breathing
Palpitations

Self-care

Take over-the-counter pain relievers or anti-inflammatories.
Use antiemetics if vomiting occurs.
Consult your physician regarding the use of anxiolytics.