Cheilitis

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Acute or chronic inflammatory states of the lips (labial submucosa) or labial commissures are called cheilitis.

It can be caused by a multiplicity of endogenous or exogenous factors, the most common being atopic dermatitis, contact irritants or allergens, chronic sun exposure and infection. Secondary involvement of the lips can occur in many skin and systemic disorders, such as lichen planus, lupus erythematosus, autoimmune blistering diseases, Crohn's disease, sarcoidosis and nutritional deficiencies. There are several types of cheilitis: angular, eczematous, actinic, glandular, granulomatous and plasma cell cheilitis.

The most common symptoms include erythema, dryness, desquamation, presence of fissures, inflammation, itching and burning.

Diagnosis is made through clinical history and physical examination.

Treatment will vary according to the type of cheilitis. It will be based on general measures such as maintaining optimal oral hygiene, use of barrier cream or petroleum jelly and medical treatment with topical corticosteroids (cream), intralesional or systemic (oral), antibiotics (in case of infection) and, depending on the evolution, surgery.

Bibliographic references
  1. Christen Mowad, MD. Cheilitis. Uptodate. Nov 02, 2015.
  2. Beth G Goldstein, MD, Adam O Goldstein, MD, MPH. Oral lesions. Uptodate. Jan 30, 2017.
  3. Rademaker M. Adverse effects of isotretinoin: A retrospective review of 1743 patients started on isotretinoin. Australas J Dermatol 2010; 51:248.
  4. Jadotte YT, Schwartz RA. Solar cheilosis: an ominous precursor: part I. Diagnostic insights. J Am Acad Dermatol 2012; 66:173.
  5. Savage NW, McKay C, Faulkner C. Actinic cheilitis in dental practice. Aust Dent J 2010; 55 Suppl 1:78.
Author
Dr. Elvira Moreno
Copyright
© TeckelMedical 2026

Symptoms

    Corner lip sores or cheilitis


    Painful chapped lips


    Reddened and/or cracked lips


    Pimples on face - Acne

Symptoms to watch out for

Fever (temperature higher than 100.4 ºF)
Painful and reddened ulcer in affected area
Reddish sores that itch, break open and ooze clear fluid or pus

Self-care

Improve oral hygiene.
Apply a cream or ointment that contains a corticosteroid.
Avoid touching festering lesions.
Reduce your intake of foods that are spicy, acidic, or very hot.