Diabetes Complications in Pregnancy - Pregestational diabetes

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Diabetes diagnosed prior to the current pregnancy; it may be type 1 diabetes, type 2 diabetes, or carbohydrate intolerance. These are characterized by the body's difficulty in adequately regulating blood glucose levels. Risk factors include obesity, family history of diabetes, and polycystic ovary syndrome.

Symptoms may include thirst, fatigue, blurred vision, and increased risk of infection.

Pre-pregnancy diagnosis includes fasting blood glucose testing and other more specific tests. Prenatal monitoring is essential to reduce the risk of complications such as congenital malformations, fetal macrosomia, neonatal hypoglycemia, and pre-eclampsia.

Treatment involves controlling blood glucose levels through diet, exercise and, in some cases, medication. It is important to follow an individualized plan of care and medical follow-up.

Bibliographic references
  1. Chaturvedi N, Stephenson JM, Fuller JH. The relationship between pregnancy and long term maternal complications in the EURODIAB IDDM Complications study. Diabet Med. 1995;12:494-9.
  2. Shub A, Lappas M. Pregestational diabetes in pregnancy: Complications, management, surveillance, and mechanisms of disease-A review. Prenat Diagn. 2020 Aug;40(9):1092-1098. doi: 10.1002/pd.5718. Epub 2020 May 23. PMID: 32333803.
  3. Cleary EM, Thung SF, Buschur EO. Pregestational Diabetes Mellitus. 2021 Jul 26. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 34370429.
  4. Ali DS, Davern R, Rutter E, Coveney C, Devine H, Walsh JM, Higgins M, Hatunic M. Pre-Gestational Diabetes and Pregnancy Outcomes. Diabetes Ther. 2020 Dec;11(12):2873-2885. doi: 10.1007/s13300-020-00932-9. Epub 2020 Oct 3. PMID: 33010001; PMCID: PMC7644712.
Author
Dra. Maria Eugenia Rodriguez
Copyright
© TeckelMedical 2026

Symptoms

    Frequent urination


    Urinate a lot at night


    Thirst


    Passing large amounts of urine


    Feeling of hunger

Symptoms to watch out for

Coke-like or dark colored urine
If it is accompanied by seizures
A feeling of shortness of breath
Vomiting
Severe belly pain
Blurry vision

Self-care

Eat a balanced diet: increase consumption of fruits, vegetables, and white meats, and reduce consumption of fatty and fried foods.
Get regular physical activity at least 3 times a week that is appropriate for your age and physical condition.
Reduce tobacco consumption.
Wear comfortable shoes that are not too tight.
Lose weight if you are overweight or obese.
Consult with your general practitioner for the indication of medication to control blood glucose and insulin levels