Dyspepsia, also known as indigestion, is a term that refers to a group of symptoms, including pain, a burning sensation, and a feeling of fullness in the upper abdomen.
The cause of this condition is unknown for most patients. In some cases, symptoms may occur after overeating or taking certain medications. It is also possible that psychological problems, such as stress, anxiety, or depression, are the cause. Other possible causes include smoking, eating foods high in fiber, and consuming too much caffeine.
The main symptom is discomfort in the upper abdomen during or after meals, described as a burning sensation between the navel and lower sternum. Other symptoms include an uncomfortable feeling of bloating when starting to eat or afterwards. Other symptoms may include abdominal distension or nausea.
A diagnosis is made through a medical history and physical examination. Additional tests may include an abdominal ultrasound and an esophagogastroduodenoscopy.
In most cases, treatment is unnecessary. If symptoms do not resolve on their own, treatment focuses on dietary guidelines, taking antibiotics (if you have Helicobacter pylori), and administering acid-reducing medications.
- George F Longstreth, MD, Brian E Lacy, MD, PhD. Approach to the adult with dyspepsia. Uptodate. Jan 19, 2017.
- Stanghellini V, Chan FK, Hasler WL, et al. Gastroduodenal Disorders. Gastroenterology 2016; 150:1380.
- Ford AC, Forman D, Bailey AG, et al. Effect of dyspepsia on survival: a longitudinal 10-year follow-up study. Am J Gastroenterol 2012; 107:912.
- Van Zanten SV, Wahlqvist P, Talley NJ, et al. Randomised clinical trial: the burden of illness of uninvestigated dyspepsia before and after treatment with esomeprazole--results from the STARS II study. Aliment Pharmacol Ther 2011; 34:714.
- Lacy BE, Weiser KT, Kennedy AT, et al. Functional dyspepsia: the economic impact to patients. Aliment Pharmacol Ther 2013; 38:170.

