Favism (Pediatrics - PEDS)

Anemia caused by an inherited deficiency of the glucose-6-phosphate dehydrogenase molecule, which leads to the destruction of red blood cells.

It can be triggered by infection, severe stress, medications (aspirin, anti-inflammatory drugs, etc.) and/or foods, including beans. 

It usually causes no symptoms, although anemia may present with paleness, weakness, and dizziness. It is sometimes associated with fever and dark urine.

Diagnosis is based on clinical interview, physical examination, blood analysis, urinalysis, and blood tests (peripheral blood smear and crossmatch).

Treatment is based on stopping the cause, if known. Transfusions may be necessary. If there are signs of infection, antibiotics may be added to the treatment.