Genital warts due to human papillomavirus - Genital condylomas

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Human papillomavirus (HPV) is a microorganism that causes genital warts and is classified as high and low risk according to its ability to cause cancer.

It is considered a sexually transmitted disease. It is spread by oral, vaginal or anal contact with an infected person. Virtually all sexually active men and women contract it at some point in their lives.

Condylomas are usually asymptomatic lesions. However, they can cause itching, stinging, swelling, a feeling of irritation and less frequently pain or even bleeding with sexual intercourse. Frequently, warts or raised lesions of varying size are observed with a rough surface, taking on a shape reminiscent of a cauliflower. In men, warts may appear on the tip or shaft of the penis, anus or scrotum. In women, they may appear on the vulva and perineal area, and extend into the vagina and cervix. However, they can also appear in the throat and mouth of a person who has had oral sex with an infected person.

Diagnosis is clinical by questioning and physical examination. There is no specific test to detect if the individual is infected by HPV. In women, it is very important to have regular check-ups to prevent it from progressing to cervical cancer.

There are several treatments aimed at eliminating warts: cryotherapy, electrocautery or surgical removal. Cytotoxic or immunomodulatory drugs can also be used and applied to the lesions.

There is a vaccine that protects both men and women from infection.

Bibliographic references
  1. Joel M Palefsky, Ross D Cranston. Virology of human papillomavirus infections and the link to cancer. UpToDate May 10, 2015.
  2. Joel M Palefsky. Epidemiology of human papillomavirus infections. UpToDate Mar 14, 2016.
  3. Barr E, Tamms G. Quadrivalent human papillomavirus vaccine. Clin Infect Dis 2007; 45:609.
  4. de Sanjose S, Quint WG, Alemany L, et al. Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study. Lancet Oncol 2010; 11:1048.
  5. Schiffman M, Wentzensen N, Wacholder S, et al. Human papillomavirus testing in the prevention of cervical cancer. J Natl Cancer Inst 2011; 103:368.
  6. Aaron C Ermel, Darron R Brown. Infecciones por el virus del papiloma humano. Harrison. Principios de Medicina Interna. Volumen 2. 19º Edición. 1197:1201
  7. Genital Warts. Leslie SW, Sajjad H, Kumar S. 2021 Jul 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan
  8. Human Papillomavirus and Genital Warts: A Review of the Evidence for the 2015 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines. Park IU, Introcaso C, Dunne EF. Clin Infect Dis. 2015 Dec 15;61 Suppl 8:S849-55. doi: 10.1093/cid/civ813.
  9. Genital warts. Steben M, Garland SM. Best Pract Res Clin Obstet Gynaecol. 2014 Oct;28(7):1063-73. doi: 10.1016/j.bpobgyn.2014.07.002. Epub 2014 Jul 17.
Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Genital wart


    Genital protuberances which cluster together to form a cauliflower-like shape


    Genital wart soft to the touch


    Small protuberance on the glans


    Small protuberances on the vulva

Symptoms to watch out for

Bleeding in the wound
Change in coloration
Pain that interferes with daily life
Wart is persistent or multiplies
History of immunodeficiency (HIV, Diabetes Mellitus, oncological disorders, long-term corticosteroid consumption).

Self-care

Avoid scratching, squeezing, or "bursting" the wart.
Consult your doctor about treatments such as cryotherapy, laser or surgical removal.
Avoid sexual intercourse and, if you do have sex, use barrier methods such as condoms.