Hand, foot and mouth disease - Human aphthous fever (Pediatrics - PEDS)

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Common-
The hand, foot and mouth disease is an infectious frequent, mild disease affecting particularly children between the ages of 1 and 5 years. It usually lasts 3-5 days. It is caused by several viruses of the family of the enterovirus. The hand, foot and mouth disease usually has the following symptoms: mouth ulcers, blisters or pimples on the hands and/or feet, low grade fever or fever and irritability. The diagnosis is achieved through physical examination by a pediatrician, and does not usually require additional tests. The treatment is symptomatic (with Paracetamol/Acetaminophen and/or Ibuprofen), soft, cold food and drinking fluids).
Bibliographic references
  1. American Academy of Pediatrics. Enterovirus (nonpoliovirus). In: Red Book: 2015 Report of the Committee on Infectious Diseases, 30th, Kimberlin DW, Brady MT, Jackson MA, Long SS. (Eds), American Academy of Pediatrics, Elk Grove Village, IL 2015. p.333.
  2. Stellrecht KA, Lamson DA, Romero JR. Enteroviruses and parechoviruses. In: Manual of Clinical Microbiology, 11th, Jorgensen JH, Pfaller MA, Carroll KC, et al. (Eds), American Society for Microbiology, Washington, DC 2015. p.1536.
  3. Nelson textbook of pediatrics. Robert M. Kliegman, Bonita F. Stanton, Joseph W. St. Geme, III, Nina F. Schor ; editor emeritus, Richard E. Behrman (2016).
  4. A guide to clinical management and public health response for hand, foot, and mouth disease (HFMD) / World Health Organization, Western Pacific Region, Regional Emerging Diseases Intervention Centre (2011).
Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Fever / Feel very hot


    Blisters larger than 0.5 cm / 0.2 inches


    Small pimples in genital and/or buttock area


    Reddening and/or rash around the mouth


    Whine

Symptoms to watch out for

Signs of dehydration: more tiredness than usual, dizziness, dry mouth and tongue.
Headache
If it is accompanied by seizures

Self-care

Use over-the-counter analgesics and antipyretics for muscle pain or fever (temperature > 100.4 F).
Drink milk, cold water, eat ice cream or cold desserts.
Eat soft foods, such as toast or crackers.