It is a complication of type 2 diabetes that involves an extremely high level of sugar (glucose) in the blood without the presence of ketones.
The condition can be caused by other diseases, infections, dehydration states and medications that decrease the effect of insulin.
It presents with increased thirst, nausea, dry mucous membranes, fever and/or convulsions.
Diagnosis is made by clinical history, complete physical examination and by the usual complementary tests (blood tests, cultures).
The aim of treatment is to correct water loss and blood glucose levels, to ensure support measures to maintain vital signs and to palliate symptoms.
- Irl B Hirsch, MD, Michael Emmett, MD. Diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults: Epidemiology and pathogenesis. UpToDate. Jul 05, 2016.
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- Irl B Hirsch, MD, Michael Emmett, MD. Diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults: Treatment. UpToDate. Dec 07, 2015.
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