Pertussis (whooping cough) is an acute respiratory infection caused by a bacterium called Bordetella pertussis.
It is a highly contagious infection (especially in unvaccinated people). Pertussis is transmitted from person to person through small respiratory droplets that contain the bacterium. These droplets are expelled by the sick person and then move through the air, facilitating its spread. Pertussis is an illness that usually lasts several weeks.
The symptoms that appear are divided into 3 distinct phases: a catarrhal phase lasting 1-2 weeks, a coughing phase lasting 2-4 weeks, and a final convalescent or remission phase lasting 1-3 weeks.
Diagnosis is based on symptoms and confirmed by a laboratory test called PCR of nasopharyngeal mucus aspirate or smear.
Treatment is with oral antibiotics. Vaccination is the main preventive measure for this disease.
- Kilgore PE, Salim AM, Zervos MJ, Schmitt HJ. Pertussis: Microbiology, Disease, Treatment and Prevention.Clin Microbiol Rev. 2016 Jul;29(3):449-86.
- Heininger U. Pertussis:what the pediatric infectious disease specialist should know. Pediatr Infect Dis J.2012 Jan;31:78-9.
- Munoz FM.Pertussis in infants, children and adolescents: diagnosis, treatment and prevention. Semin Pediatr Infect Dis. 2006 Jan;17(1):14-9. Review.
- Schellekens J, von König CH, Gardner P. Pertussis sources of infections and routes of transmissin in the vaccination era, Pediatr Infect Dis J. 2005 May;24(5 Suppl):S19-24.
- American Academy of Pediatrics. Pertussis (whooping cough). In: Red Book: 2015 Report of the Committee on Infectious Diseases, 30th ed, Kimberlin DW, Brady MT, Jackson MA, Long SS (Eds), American Academy of Pediatrics, Elk Grove Village, IL 2015. p.609.

