Infective endocarditis

Medium urgency
-Moderately severe

Endocarditis is the inflammation of the inner lining of the heart valves and chambers, called the endocardium.

It is caused by a bacterial infection or, rarely, by viruses or fungi.

Symptoms may occur suddenly (fever and rapid heart rate, fatigue) or slowly (mild fever, weight loss, excessive sweating, anemia and freckle-like skin spots on the palms of the hands, nails, soles of the feet and whites of the eyes).

Diagnosis is made by a detailed clinical history, physical examination, electrocardiogram, blood tests with cultures, chest X-ray and echocardiogram.

Treatment is based on the administration of intravenous antibiotics and medical treatment of symptoms. If there are severe complications, surgery may be required.

Bibliographic references
  1. Daniel J Sexton. Epidemiology, risk factors, and microbiology of infective endocarditis. UpToDate. Oct 29, 2015.
  2. Daniel J Sexton, Vance G Fowler, Jr. Clinical manifestations and evaluation of adults with suspected native valve endocarditis. UpToDate. Feb 10, 2016.
  3. Daniel J Sexton. Antimicrobial therapy of native valve endocarditis. UpToDate. Jul 05, 2016.
  4. Baddour LM, Wilson WR, Bayer AS, et al. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association. Circulation 2015; 132:1435.
  5. Clinical Laboratory Standards Institute. Performance Standards for Susceptibility Testing. Twenty-second informational supplement CLSI document M100-S22, vol 32. Wayne, PA 2012.
  6. Karchmer AW. Endocarditis infecciosa. Harrison. Manual de Medicina. 16º edición. 390-398.
Author
Dr. Elvira Moreno
Copyright
© TeckelMedical 2026

Symptoms

    Linear hemorrhages under the nails


    Painful red nodes on fingers and toes


    Fever between 39ºC / 102.2ºF and 39.9ºC / 103.82ºF


    Blotches on palms and soles


    Red spotting on the skin - petechiae

Pre-hospital care recommendations

Take over-the-counter pain relievers or anti-inflammatories.
Relative rest, rest until symptoms subside.