Leptospirosis

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Infection caused by a type of bacteria from the Leptospira genus.

This bacterium can affect animals such as rats, dogs, cattle, among others, and it is eliminated through urine. Humans acquire the infection by direct contact with infected animals tissue, urine or with contaminated water and/or soil.

It can appear as an occupational disease (farmers, slaughterhouse or sewage workers, sweepers, hunters, veterinarians...) or a recreational one (swimming in fresh water, kayaking-canoeing...).

It occurs mainly in tropical-subtropical areas with hot and humid climates, in the summer and autumn months.

Symptoms occur in phases:

  • High fever onset, chills, headache, severe muscle aches, dry cough, sore throat, nausea, vomiting, diarrhea, etc.
  • After 4-9 days there is a phase of apparent improvement.
  • The fever reappears, as well as possible complications, affecting kidneys, liver, nervous system, lungs and/or heart. We can observe a yellowing tinting of the skin and mucous membranes, abdominal pain and bloating, neck stiffness, impaired consciousness, chest pain and bleeds from the nasal, lung, digestive tract, urine and cutaneous hemorrhages.

The diagnosis is reached through the clinical history and a physical examination. It is confirmed by observing samples under a dark field microscope, performing cultures and serological tests-PCR.

The treatment is based on antibiotics: in less severe cases, oral ampicillin or amoxicillin are used. In more severe cases, intravenous penicillin or ampicillin and doxycycline will be used.

Bibliographic references
  1. Fry NK, La Ragione RM, Ready D. Leptospirosis. J Med Microbiol. 2019 Mar;68(3):289
  2. De Laroche M, Jauréguiberry S. Leptospirosis. Rev Prat. 2016 Oct;66(8):886-892
  3. Torres-Castro M, Hernández-Betancourt S, Agudelo-Flórez P, Arroyave-Sierra E, Zavala-Castro J, Puerto FI. Current review of the epidemiology of leptospirosis. Rev Med Inst Mex Seguro Soc. 2016 Sep-Oct;54(5):620-5
  4. Ellis WA. Animal leptospirosis. Curr Top Microbiol Immunol. 2015;387:99-137
Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Both eyes red


    Yellow tinge to skin and mucous membranes


    Shivers


    Intermittent high fever


    High fever of 40ºC/104ºF or above

Symptoms to watch out for

Headache
Neck stiffness
Urinate less than a 16 oz soft drink in 24 hours

Self-care

Take over-the-counter pain relievers or anti-inflammatories.
Use antiemetics if vomiting occurs.
Consult with your primary care physician regarding the prescription of antibiotics.