Medium urgency
-Moderately severe
Lithium is a drug used in psychiatry for the treatment of certain diseases as a mood stabilizer. There are several types: acute poisoning, chronic poisoning and acute-on-chronic poisoning. There are factors that may increase the probability of poisoning, including decreased blood electrolytes such as sodium, dehydration or taking diuretics and impaired renal function. Symptoms may include diarrhea, dizziness, nausea, abdominal pain, vomiting, weakness, hand tremors, incoordination of arms and legs, muscle fasciculations, seizures, impaired speech, uncontrollable eye movements, coma and cardiac arrhythmias that can lead to the death of the patient. The diagnosis is based on performing a detailed medical history, complete physical examination, blood and urine tests and ECG. Treatment revolves around maintaining life support measures, proper hydration, gastric lavage is performed, and blood cleansing through hemodialysis, depending on the situation.
- Jeanmarie Perrone, Pia Chatterjee. Lithium poisoning. UpToDate. Feb 05, 2015.
- Bronstein AC, Spyker DA, Cantilena LR Jr, et al. 2010 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 28th Annual Report. Clin Toxicol (Phila) 2011; 49:910.
- Meltzer, H. Antipsychotic Agents & Lithium. In: Basic and Clinical Pharmacology, 11th ed, McGraw Hill, New York 2009. p.487.
- Venkatarathnamma PN, Patil AR, Nanjundaiah N. Fatal lithium toxicity with therapeutic levels--a case report. Int J Clin Pharmacol Ther 2011; 49:336.
- Beatriz Benito, Natividad Laín Terés. Intoxicación aguda por fármacos, drogas y setas. Manual de protocolos y actuación en urgencias. Hospital Virgen de la Salud, Complejo Hospitalario de Toledo. Tercera edición. 2010. 1014:1015
- L.Marruecos Sant. Intoxicación medicamentosa aguda. Farreras Rozman. Medicina Interna. Volumen 2. 12º edición. 2533:2536.
Dr. Elvira Moreno
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