Medium urgency
-Moderately severe
The ovarian hyperstimulation syndrome consists of the over-growing of the secondary ovaries due to an increase in hormone production and is directly related to the drugs used in assisted human reproduction techniques.
The hormones administered to stimulate the ovary formation make the ovaries increase in size, can be painful and can also accumulate fluid in the abdominal area.
The main risk factors for ovarian hyperstimulation syndrome are:
- Polycystic ovary syndrome
- Under 35 years of age
- Obtaining a large number of eggs in the assisted reproduction cycle
- Being underweight
The symptoms are mild but can worsen over time, especially if pregnancy has been achieved. Usually manifests with abdominal pain and bloating, nausea and/or vomiting.
In its more severe forms the pain may be severe, the abdominal swelling more significant and there may be shortness of breath and problems in the coagulation of the blood.
Diagnosis requires a gynecological examination, a blood test and a transvaginal ultrasound. Mild ovarian hyperstimulation syndrome usually resolves spontaneously in 1-2 weeks. Moderate and severe forms may require medication or hospitalization. Exceptionally, surgery may be necessary if ovarian complications are associated (torsion, cyst rupture, bleeding, etc.).
Diagnosis requires a gynecological examination, a blood test and a transvaginal ultrasound. Mild ovarian hyperstimulation syndrome usually resolves spontaneously in 1-2 weeks. Moderate and severe forms may require medication or hospitalization. Exceptionally, surgery may be necessary if ovarian complications are associated (torsion, cyst rupture, bleeding, etc.).
- Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org; Practice Committee of the American Society for Reproductive Medicine. Prevention and treatment of moderate and severe ovarian hyperstimulation syndrome: a guideline. Fertil Steril. 2016 Dec;106(7):1634-1647. doi:10.1016/j.fertnstert.2016.08.048. Epub 2016 Sep 24. PMID: 27678032
- Petrenko AP, Castelo-Branco C, Marshalov DV, Salov IA, Shifman EM. Ovarian hyperstimulation syndrome. A new look at an old problem. Gynecol Endocrinol. 2019 Aug;35(8):651-656. doi: 10.1080/09513590.2019.1592153. Epub 2019 Apr 2. PMID: 30935259.
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