It is the growth of malignant cells in the thyroid gland, located in the anterior neck area. It is the most frequent cancer of the thyroid gland and appears preferentially in women between 30 and 50 years of age.
Its origin is unknown but it seems to have a genetic cause and a relationship with exposure to radiation. In children, it has been associated with radiotherapy treatments.
It manifests as a lump in the neck without other symptoms.
Diagnosis is clinical by examination and palpation of the anterior neck. It is confirmed by blood tests and ultrasound, with puncture sampling when the nodule is larger than 1 cm.
Treatment is usually surgical, sometimes accompanied by radioactive iodine. In inoperable cases, radiotherapy may be applied to the gland.
Subsequently, thyroid hormone replacement therapy must be taken for life.
Most thyroid nodules are benign but if you feel one you should consult a specialist to rule it out.
- R Michael Tuttle, MD. Overview of papillary thyroid cancer. UpToDate. Sep 30, 2016.
- R Michael Tuttle, MD. Differentiated thyroid cancer: Clinicopathologic staging. UpToDate.
- R Michael Tuttle, MD. Differentiated thyroid cancer: Overview of management. UpToDate. May 12, 2016.
- Jameson JL. Mandel SJ. Weetman AP. Trastornos de la glándula tiroides. Harrison. Principios de Medicina Interna. Volumen 2. 19º Edición: 2305-2307.
- Vaccarella S, Franceschi S, Bray F, et al. Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis. N Engl J Med 2016; 375:614.
- Surveillance Research Program. SEER Stat Fact Sheets: Thyroid Cancer. National Health Institute. http://seer.cancer.gov/statfacts/html/thyro.html Last access: Dec 07, 2016.
- Davies L, Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg 2014; 140:317.
