Inflammation of the sac-like layer that surrounds and protects the heart.
It has many causes: infectious, neoplastic, autoimmune, renal insufficiency, hypothyroidism, etc.
It manifests as a sharp pain in the chest that can radiate to the neck, shoulders, back, or abdomen. It gets worse when you lie down, take a deep breath, cough, or swallow. It usually improves with sitting down and bending forward.
Diagnosis is based on your medical history, a physical examination, an electrocardiogram, and may require an imaging test such as a chest x-ray or echocardiogram.
If a viral cause is suspected, rest and anti-inflammatory treatment may be sufficient. If a bacterial cause is suspected, antibiotic treatment and occasional draining of the fluid will be needed. In other situations, treatment depends on the underlying condition.
A patient with uncomplicated acute pericarditis may be treated as an outpatient. However, high-risk patients (high fever, significant pericardial effusion, heart failure, and failure to respond to anti-inflammatory therapy) should be admitted to the hospital for evaluation.
- Massimo Imazio, MD, FESC. Clinical presentation and diagnostic evaluation of acute pericarditis. Up ToDate. Feb 02, 2016.
- Imazio M. Contemporary management of pericardial diseases. Curr Opin Cardiol 2012; 27:308.
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- Kytö V, Sipilä J, Rautava P. Clinical profile and influences on outcomes in patients hospitalized for acute pericarditis. Circulation 2014; 130:1601.
- Imazio M, Gaita F, LeWinter M. Evaluation and Treatment of Pericarditis: A Systematic Review. JAMA 2015; 314:1498.

