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This is a disease in which calcium pyrophosphate crystals are deposited in the cartilage of the joints. The cause is generally unknown, although it is known that it has an associated genetic origin and that there are conditions that may trigger it and that are likely to be associated. In the majority of cases, there are no symptoms. If there are any, they are characterized by acute episodes of arthritis with heat, flushing and increased articular volume. It is diagnosed by taking a detailed medical history, examining the joint and after obtaining a sample of joint fluid showing the existence of calcium pyrophosphate crystals. Treatment is based on nonsteroidal anti-inflammatory drugs, corticosteroids and/or colchicine, in addition to the removal of crystals by fine-needle aspiration of joint fluid and sometimes surgical treatment.
- Michael A Becker, Lawrence M Ryan. Clinical manifestations and diagnosis of calcium pyrophosphate crystal deposition (CPPD) disease. UpToDate. Jul 14, 2015.
- Michael A Becker, Lawrence M Ryan. Pathogenesis and etiology of calcium pyrophosphate crystal deposition (CPPD) disease. UpToDate. Sep 10, 2015.
- Michael A Becker, Lawrence M Ryan. Treatment of calcium pyrophosphate crystal deposition (CPPD) disease. UpToDate. Sep 22, 2016.
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- Reginato AJ. Gota y otras artropatías microsalinas. Harrison. Manual de Medicina. 16º edición. 849-850.
Dr. Elvira Moreno
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