It is a chronic and generalized inflammation of the joints, predominantly of small joints such as fingers and wrists.
The cause is unknown but a combination of genetic predisposition, autoimmunity and environmental factors is suggested.
It manifests with pain, swelling and joint stiffness. The involvement is symmetrical and can lead to joint deformity. Muscle pain, fever and weight loss are frequently added.
Diagnosis is clinical, based on interrogation and physical examination. It will be completed with blood tests, radiographs and other imaging tests.
The aim of treatment is to reduce pain and inflammation with analgesics and anti-inflammatory drugs. In many cases, immunosuppressive medication will be added in order to slow the progression of the disease.
- PJW Venables. Clinical manifestations of rheumatoid arthritis. UpToDate. Agosto. 2016
- Larry W Moreland. General principles of management of rheumatoid arthritis in adults. UpToDate. Julio. 2016
- Singh JA. 2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken) 2012; 64:625.
- Smolen JS. Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis 2010; 69:631.
- Ankoor Shah. Artritis reumatoide. Harrison. Principios de Medicina Interna, 19e. Capítulo 380
