Systemic gonococcal infection

Medium urgency
-Moderately severe

Disseminated gonococcal infection results from the spread through blood circulation of the bacterium Neisseria gonorrhoeae. It is considered a sexually transmitted infection.

It initially infects the mucosa of the urethra, uterus, rectum or mouth, and from there, it passes into the bloodstream to infect the rest of the organs.

Predisposing to infection are: menstruation, pregnancy, recent childbirth, and sexual promiscuity. An increased incidence has been described in non-white, low socioeconomic status, homosexuals or in persons who habitually consume drugs.

It manifests with painful joint inflammation, tendon and skin inflammation. It is usually accompanied by fever, chills and general malaise.

The most affected joints are the knees, elbows, wrists and ankles. It is characteristic that it affects joints asymmetrically. 

It is diagnosed by clinical history, complete physical examination and by blood and joint fluid cultures. 

Treatment is based on intravenous antibiotherapy. Sexual partners of patients should receive the same treatment.

Bibliographic references
  1. Don L Goldenberg, Daniel J Sexton. Disseminated gonococcal infection. UpToDate. Sep 12, 2016.
  2. Belkacem A, Caumes E, Ouanich J, et al. Changing patterns of disseminated gonococcal infection in France: cross-sectional data 2009-2011. Sex Transm Infect 2013; 89:613.
  3. Phupong V, Sittisomwong T, Wisawasukmongchol W. Disseminated gonococcal infection during pregnancy. Arch Gynecol Obstet 2005; 273:185.
  4. Kühlewein C, Rechner C, Meyer TF, Rudel T. Low-phosphate-dependent invasion resembles a general way for Neisseria gonorrhoeae to enter host cells. Infect Immun 2006; 74:4266.
  5. Read P, Abbott R, Pantelidis P, et al. Disseminated gonococcal infection in a homosexual man diagnosed by nucleic acid amplification testing from a skin lesion swab. Sex Transm Infect 2008; 84:348.
  6. Ram S, Rice PA. Infecciones gonocócicas. Harrison. Manual de Medicina. 16º edición. 418-422.
Author
Dr. Elvira Moreno
Copyright
© TeckelMedical 2026

Symptoms

    Joint swelling


    Skin rash


    Pus discharge from the urethra of the penis


    Fever / Feel very hot


    Genital vesicles which produce painful sores

Pre-hospital care recommendations

Relative rest, rest until symptoms subside.
Take over-the-counter pain relievers or anti-inflammatories.