Tonsillopharyngitis due to diphtheria

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Tonsillopharyngitis diphtheria is a bacterial infection of the pharynx and tonsils caused by Corynebacterium diphtheriae. It is transmitted by direct contact with the skin of the infected person, as well as by contact with secretions from the airways. It manifests as a sore throat, slight increase in body temperature and inflamed lymph nodes in the neck, false membranes composed of fibrin firmly attached to the pharynx and tonsils, called pseudomembranes, are typically formed. Diagnosis will be made by taking a medical history and performing a physical examination (pharyngeal inflammation and attached membranes). Medical treatment is based on antibiotics, proper hydration, analgesia and a diphtheria antitoxin. Monitoring the patient’s airway, vital signs and neurological status is important. The patient must remain in respiratory and contact isolation.
Bibliographic references
  1. Luis F Barroso, Samuel Pegram. Clinical manifestations, diagnosis, and treatment of diphtheria. UpToDate. Oct 04, 2016.
  2. Luis F Barroso, Samuel Pegram. Epidemiology and pathophysiology of diphtheria. UpToDate. Feb 24, 2016.
  3. Jayashree M, Shruthi N, Singhi S. Predictors of outcome in patients with diphtheria receiving intensive care. Indian Pediatr 2006; 43:155.
  4. Sing A, Heesemann J. Imported cutaneous diphtheria, Germany, 1997-2003. Emerg Infect Dis 2005; 11:343.
  5. Soriano F. Infecciones por Corynebacterium. Farreras Rozman. Medicina Interna. Volumen 2. 12º edición: 2265-2269.
Author
Dr. Elvira Moreno
Copyright
© TeckelMedical 2026

Symptoms

    Greyish-white membranes in the throat


    Sore throat


    Pharyngeal membranes bleeding when detached


    Swollen nodes on the neck


    Red or swollen tonsils

Symptoms to watch out for

Fever not relieved by antipyretics (paracetamol, ibuprofen)
One-sided neck swelling and pain
Difficulty breathing
Difficulty swallowing
Difficulty opening the mouth

Self-care

Relative rest, rest until symptoms subside.
Maintain a fluid intake of 6 - 8 cups per day.
Consult with your primary care physician regarding the prescription of antibiotics.
Consume beverages and foods that help relieve pain (tea, soup, honey, etc.).
Use over-the-counter analgesics and antipyretics for muscle pain or fever (temperature > 100.4 F).
Consult your primary care practitioner regarding the prescription of diphtheria antitoxin.