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Inflammation of the meninges that surround the brain to protect it, caused by infection by the bacterium Mycobacterium tuberculosis. It typically manifests with a headache and stiffness of the neck muscles, but it is accompanied by stupor and coma in many cases. Diagnosis is clinical and made through an analysis of cerebrospinal fluid. Treatment with tuberculostatics must be started early to avoid coma states and neurological deficits. It is considered a medical emergency, so it is therefore necessary to urgently attend an accident and emergency department.
- John M Leonard. Central nervous system tuberculosis. UpToDate, Sep 12, 2016.
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- Vadwai V, Boehme C, Nabeta P, et al. Xpert MTB/RIF: a new pillar in diagnosis of extrapulmonary tuberculosis? J Clin Microbiol 2011; 49:2540.
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- Karen L. Roos, Kenneth L. Tyler. Meningitis, encefalitis, absceso cerebral y empiema. Harrison. Principios de Medicina Interna. Volumen 2. 19ª Edición. 883:899
- Walter J. Koroshetz, Avindra Nath. Meningitis crónica y recurrente. Harrison. Principios de Medicina Interna. Volumen 2. 19ª Edición. 906:911.
- Elena Sánchez Maganto, Agustín Julián Jiménez. Infecciones del sistema nervioso central. Manual de protocolos y actuación en urgencias. Hospital Virgen de la Salud, Complejo Hospitalario de Toledo. Tercera edición. 2010. Capítulo 697:716.
Dr. Oscar Garcia-Esquirol
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