Typhoid fever

Medium urgency
-Moderately severe

Infection caused by a bacterium called Salmonella typhi, which infects the body via the digestive tract. It most commonly affects children and young adults. It is prevalent in Central and Southwest Asia, South America and sub-Saharan Africa.

The infected person can become a carrier, releasing the bacteria in their feces for years. Infection occurs when food and drink contaminated with human fecal products are ingested.

It presents with the triad of fever, skin changes and diarrhea. Characteristically, the fever is high and the diarrhea is intense, leaving the person with significant impairment of general condition.

Diagnosis is based on clinical examination, physical examination and blood and stool cultures.

Treatment includes proper hydration and antibiotics. It is essential to prevent infection by drinking bottled water, eating cooked food and by proper vaccination if travelling to endemic areas.

Bibliographic references
  1. Elizabeth L Hohmann. Epidemiology, microbiology, clinical manifestations, and diagnosis of typhoid fever. UpToDate. Agosto 2016
  2. Parry CM. Typhoid fever. N Engl J Med 2002; 347:1770.
  3. Elizabeth L Hohmann. Treatment and prevention of typhoid fever. UpToDate. Octubre 2016
  4. Vollaard AM. Identification of typhoid fever and paratyphoid fever cases at presentation in outpatient clinics in Jakarta, Indonesia. Trans R Soc Trop Med Hyg 2005; 99:440.
  5. Jay S. Keystone. Recomendaciones de salud para viajes internacionales. Harrison. Principios de Medicina Interna, 19e. Capítulo 149
  6. David A. Pegues. Salmonelosis. Harrison. Principios de Medicina Interna, 19e. Capítulo 190
Author
Dr. Patricia Sánchez
Copyright
© TeckelMedical 2026

Symptoms

    Faster breathing rate


    Fever / Feel very hot


    Feeling generally unwell


    Pain in lower right abdomen


    Increase in abdominal size

Pre-hospital care recommendations

Maintain a fluid intake of 6 - 8 cups per day.
Relative rest, rest until symptoms subside.