Ulcerative colitis - Inflammatory bowel disease

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It is a disease in which ulcers are formed by the destruction of the internal wall of the large intestine, mainly the final part of the colon and rectum. It is more frequent between 15 and 40 years of age. 

The causes are unknown, although a hereditary component is attributed to it.

It manifests with abdominal pain and bloody diarrhea. It may be accompanied by weight loss, fatigue, lack of appetite, dehydration and/or bleeding from the rectum.

Diagnosis is made by a detailed clinical history, focusing on bowel habits and other possible causes for the symptoms. The diagnosis of certainty will be made by colonoscopy.

Treatment includes different types of medications that can be taken alone or in combination: aminosalicylates, corticosteroids, anti-inflammatory drugs and immunosuppressive agents.

It is not a medical emergency but you should consult your physician to obtain a diagnosis of certainty and initiate treatment.

Bibliographic references
  1. Mark A Peppercorn, Sunanda V Kane. Clinical manifestations, diagnosis, and prognosis of ulcerative colitis in adults. UpToDate Sep 07, 2016
  2. Satsangi J, Silverberg MS, Vermeire S, Colombel JF. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 2006; 55:749.
  3. Samuel S, Bruining DH, Loftus EV Jr, et al. Validation of the ulcerative colitis colonoscopic index of severity and its correlation with disease activity measures. Clin Gastroenterol Hepatol 2013; 11:49.
  4. Jess T, Frisch M, Simonsen J. Trends in overall and cause-specific mortality among patients with inflammatory bowel disease from 1982 to 2010. Clin Gastroenterol Hepatol 2013; 11:43.
  5. Bewtra M, Kaiser LM, TenHave T, Lewis JD. Crohn's disease and ulcerative colitis are associated with elevated standardized mortality ratios: a meta-analysis. Inflamm Bowel Dis 2013; 19:599.
  6. J Vilaseca, F Casellas, F Guarner. Enfermedad inflamatoria del intestino. Farreras Rozman. Medicina Interna. Volumen 1. 12º edición. 169:182.
  7. Sonia Friedman, Richard S Blumberg. Enfermedad intestinal inflamatoria. Harrison. Principios de Medicina Interna. Volumen 2. 19º Edición. 1947:1965.
Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Stools with fresh blood


    Black stools


    Diarrhea with blood


    Pus in stools


    Lower left abdominal pain

Symptoms to watch out for

Fever (temperature higher than 100.4 ºF)
Severe abdominal pain, which does not allow you to perform activities of daily living
Blood in stool

Self-care

It is recommended to follow a balanced diet, consume water-soluble fiber (fruits and vegetables), avoid gas-producing foods (beans, cabbage, cauliflower, broccoli), carbonated beverages with preservatives, synthetic sweeteners and refined sugar.
Maintain a fluid intake of 6 - 8 cups per day.
Get regular physical activity at least 3 times a week that is appropriate for your age and physical condition.
Reduce situations that cause psychological stress
If you have diarrhea, talk to your doctor about prescribing antidiarrheal medicine.
Take over-the-counter pain relievers or anti-inflammatories.
Reduce tobacco consumption.
Consult with your general practitioner for the indication of corticosteroids, immune system inhibitors and/or biological drugs.