Acute confusional syndrome - Delirium

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Acute confusional state also known as “delirium”, corresponds to a change in mental state that is characterised by being acute and reversible.

It is the result of a primary brain injury or caused by a systemic or neurological disease, intoxication or withdrawing toxic agents or drugs.

It can manifest in a very varied and striking manner, with altered attention span, altered perception, etc.

Diagnosis will be made by means of the clinical history and performing a full physical examination, including an attention test. It may be necessary to perform other laboratory or imaging tests.

Treatment is based on three prevention pillars, specific treatment and supportive treatment.

Bibliographic references
  1. Joseph Francis, Jr. Delirium and acute confusional states: Prevention, treatment, and prognosis. UpToDate. Aug 13, 2014.
  2. Clegg A, Siddiqi N, Heaven A, et al. Interventions for preventing delirium in older people in institutional long-term care. Cochrane Database Syst Rev 2014; :CD009537.
  3. Reston JT, Schoelles KM. In-facility delirium prevention programs as a patient safety strategy: a systematic review. Ann Intern Med 2013; 158:375.
  4. Van Rompaey B, Elseviers MM, Van Drom W, et al. The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients. Crit Care 2012; 16:R73.
  5. Clegg A, Young JB. Which medications to avoid in people at risk of delirium: a systematic review. Age Ageing 2011; 40:23.
  6. Bird TD, Miller BL. Demencias primarias. Harrison. Manual de Medicina. 16º edición. 959-966.
  7. Quintero Gutiérrez del älamo, Chinchilla Moreno. El Cuadro confusional agudo. Manual de Urgencias Psiquiátricas. Capítulo 12. Pág: 299-309.
Author
Dr. Elvira Moreno
Copyright
© TeckelMedical 2026

Symptoms

    Difficulty orientating oneself


    Mental disconnection


    Acute change in mental state


    Diminished level of consciousness


    Difficulty to sustain attention

Pre-hospital care recommendations

Maintain hydration of 2 litres per day.
Remain calm.
Do not leave the person suffering from the disease alone.