Worsening of chronic airflow limitation due to increased inflammation and mucus in the airways.
The most common cause of decompensation is viral or bacterial respiratory infection.
It manifests as an increase in regular coughing and sputum production, which may be accompanied by a progressive deterioration in breathing capacity and wheezing.
It is diagnosed by a medical history and physical examination.
A blood test with blood gases and a lung imaging test, usually an X-ray, will be done.
The cause should be treated early, with antibiotic therapy started if bacteria are responsible. In more severe cases, lung ventilation may be required to ensure the correct levels of oxygen and carbon dioxide in the blood.
It is a chronic condition that causes many consultations and hospital admissions for exacerbations of the underlying condition.
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- Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2016. www.goldcopd.org (Accessed on March 17, 2016).
- Buist AS, McBurnie MA, Vollmer WM, et al. International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. Lancet 2007; 370:741.
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