It is a loss of brain function that affects memory, thinking and behaviour. It is the most common form of dementia, is incurable and tends to affect people over the age of 65.
Although the exact cause is unknown, certain genes have been described that are associated with the disease.
Onset may be marked by episodes of forgetfulness due to recent memory loss. Other symptoms may also appear, such as difficulty performing tasks that were once simple, difficulty solving problems, mood or personality changes that may be mistaken for depression, changes in sleep patterns, and an inability to remember people, places and events. Very advanced cases are characterised by problems with basic activities of daily living, such as eating, dressing and bathing, understanding language, etc.
Diagnosis is made clinically by interview, physical examination and tests to assess mental status. Additional tests may be done to rule out other possible causes of dementia.
There is no cure for dementia caused by Alzheimer's disease. However, there are therapies and medications that can slow the progression of symptoms.
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- William W. Seeley. Enfermedad de Alzheimer y otras demencias. Harrison. Principios de Medicina Interna, 19e. Capítulo 448
- R. Blesa González. Enfermedad de Alzheimer y otras demencias degenerativas. Farreras Rozman. Medicina Interna, ed 18. Capítulo 175

