Thickening of the interdigital nerve in the space between the third and fourth toes.
The exact cause is unknown. Its risk factors include wearing tight shoes and high heels, positioning the fingers abnormally, flat feet, forefoot problems (bunions and hammertoes) and/or high arches. It is more common in women than in men.
Symptoms may include tingling, cramping, severe pain that increases when wearing shoes or pressing on the area and that worsens over time.
The diagnosis is reached through the medical history and physical examination of the foot, confirmed by imaging tests such as a high-resolution ultrasound or MRI.
Treatment is based on foot protection (orthesis, changing the shoes) and pain control with anti-inflammatories and painkillers. In some cases, surgery may be needed to remove the thickened tissue and inflamed nerve.
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