Bacterial meningitis in neonates (Paediatrics)

Medium urgency
-Moderately severe

This is an infection of the layers that surround and protect the brain and spinal cord, called the meninges.

Bacterial meningitis is more common in the first month of life than at any other time. The most common cause in neonates is the Streptococcus agalactiae and E. coli. From three months old onwards the Meningococcus, pneumococcus and H. influenzae.

Neurological symptoms include irritability, lethargy, tremors, seizures and a bulging fontanelle. In newborn infants, the most common symptom is an unstable temperature, from fever to hypothermia.

Diagnosis is suspected by the clinical history and physical examination. Additional tests such as laboratory tests, lumbar puncture, blood cultures and cerebrospinal fluid cultures, a CT-scan and/or MRI scan will be required.

Treatment is with antibiotics and must be started as soon as possible once the disease is suspected. It will be treated in an intensive care unit.

Bibliographic references
  1. Sheldon L Kaplan. Bacterial meningitis in children older than one month: Clinical features and diagnosis. UpToDate. Noviembre 2015
  2. Sheldon L Kaplan. Bacterial meningitis in children older than one month: Treatment and prognosis. UpToDate. Junio 2015
  3. Morven S Edwards. Bacterial meningitis in the neonate: Clinical features and diagnosis. UpToDate. Enero 2016
  4. Morven S Edwards. Bacterial meningitis in the neonate: Treatment and outcome. UpToDate. Enero 2016
  5. Karen L. Roos. Meningitis, encefalitis, absceso cerebral y empiema. Harrison. Principios de Medicina Interna, 19e. Capítulo 164
Author
Dr. Patricia Sánchez
Copyright
© TeckelMedical 2026

Symptoms

    Neck stiffness


    Bulging infant skull - Bulging fontanelle


    Eating very little and/or refusing to eat


    Feeling downcast


    Whine

Pre-hospital care recommendations

Consume over-the-counter pain relievers or anti-inflammatories.
Consume antiemetics if vomits are present.
Remain calm.
If there are seizures it is important for the person not to hit their head. Turn them onto their side and don't introduce any objects or hands in their mouth.