Bacterial meningitis

Medium urgency
CommonModerately severe

It is an infection of the layers that surround and protect the brain and spinal cord, called the meninges.

The most common bacteria involved are: Meningococcus, Pneumococcus, Group B Streptococcus and Haemophilus influenzae. In patients between 50 and 60 years of age with cellular immunodeficiency, the most frequent bacterium is Listeria monocytogenes. Risk factors or situations that favour the appearance of meningitis are sinusitis, otitis media, diabetes, alcoholism, absence of spleen, and craniocerebral trauma with cerebrospinal fluid leaking from the nose (rhinorrhoea).  

It typically manifests with fever, headache, neck muscle stiffness and altered mental status. Other associated symptoms are nausea and vomiting, drowsiness, confusion, convulsions, irritability, photophobia, etc. When the cause is meningococcus, skin lesions may appear.

Diagnosis is based on clinical history and physical examination, and is confirmed by analysis of cerebrospinal fluid.

Treatment is early antibiotic treatment, combined with corticosteroids if pneumococcal or H. influenzae meningitis is suspected. Antipyretics will be added to control fever, anticonvulsants if seizures occur, and serum therapy to maintain vital signs.

Bibliographic references
  1. Karen L. Roos, Kenneth L. Tyler. Meningitis, encefalitis, absceso cerebral y empiema. Harrison. Principios de Medicina Interna. Volumen 2. 19ª Edición. 885:892.
  2. Scheld WM, Koedel U, Nathan B, Pfister HW. Pathophysiology of bacterial meningitis: mechanism(s) of neuronal injury. J Infect Dis 2002; 186 Suppl 2:S225.
  3. Van de Beek D, de Gans J, Spanjaard L, et al. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med 2004; 351:1849.
  4. Allan R Tunkel. Clinical features and diagnosis of acute bacterial meningitis in adults. UpToDate. Aug 17, 2016.
  5. J. García San Miguel. Meningitis. Farreras Rozman. Medicina Interna. Volumen II. Duodécima edición. 1381:1384.
Author
Dr. Oscar Garcia-Esquirol
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© TeckelMedical 2026

Symptoms

    Coma


    Diminished level of consciousness


    Neck stiffness


    Bothered by light


    Drowsiness

Pre-hospital care recommendations

Consume over-the-counter pain relievers or anti-inflammatories.
Consume antiemetics if vomits are present.
If there are seizures it is important for the person not to hit their head. Turn them onto their side and don't introduce any objects or hands in their mouth.
Remain calm.