Cholangitis - Biliary sepsis

Medium urgency
-Moderately severe

Cholangitis is an inflammation of the duct that carries bile from the liver to the gallbladder and intestines.

The main cause is a bacterial infection, usually caused by a stone that blocks the bile duct.

The most common symptoms are: fever, yellowing of the skin and abdominal pain.

The diagnosis is made clinically by interview and physical examination. Diagnosis is confirmed by blood tests and imaging tests, usually ultrasound and/or CT-scan.

Treatment includes fasting, adequate intravenous hydration and antibiotic therapy. If the situation does not improve, the bile duct may need to be drained by endoscopy (retrograde cholangiopancreatography), by placing a drain through the skin (percutaneous biliary drainage) or by surgery.

Bibliographic references
  1. Nezam H Afdhal. Acute cholangitis. UpToDate. Mar 18, 2016.
  2. Kimura Y, Takada T, Kawarada Y, et al. Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 2007; 14:15.
  3. Kiriyama S, Takada T, Strasberg SM, et al. TG13 guidelines for diagnosis and severity grading of acute cholangitis (with videos). J Hepatobiliary Pancreat Sci 2013; 20:24.
  4. Norton J. Greenberger, Gustav Paumgarther. Enfermedades de la vesícula biliar y las vías biliares. Harrison. Principios de Medicina Interna. Volumen 2. 19º Edición. 2075- 2086
  5. E. Ros. Enfermedades de las vías biliares. Farreras Rozman. Medicina Interna. Volumen 1. 12º edición. 360-362.
  6. María García Ávila, Ángel Blanco Bravo. Patología urgente de la vía biliar. Manual de protocolos y actuación en Urgencias. 3ª edición. 2010.450- 452.
Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Localised abdominal pain


    Yellow tinge to skin and mucous membranes


    Upper right abdominal pain


    Fever / Feel very hot


    Shivers