Coeliac disease

Low urgency
Common-

Chronic disease of the digestive system characterised by a permanent intolerance to gluten.

The cause of celiac disease is unknown, although environmental, genetic and immune factors appear to contribute to its development.

It affects each person differently, ranging from a complete absence of symptoms to a variety of clinical manifestations, the most common of which are diarrhoea, weight loss, anaemia, frequent bowel movements (soft, fatty, pale and foul-smelling stools), abdominal pain and swelling, bloating, indigestion and mood changes.

The diagnosis is made by clinical interview, physical examination, specific blood tests (e.g. for certain antibodies) and a biopsy of the small intestine.

The basis of treatment is the complete elimination of gluten for life.

Bibliographic references
  1. Detlef Schuppan, Walburga Dieterich. Pathogenesis, epidemiology, and clinical manifestations of celiac disease in adults. UpToDate. Jun 18, 2015
  2. Ciarán P Kelly. Diagnosis of celiac disease in adults. UpToDate. Jun 18, 2015
  3. Paul J Ciclitira. Management of celiac disease in adults. UpToDate. Jun 01, 2015
  4. Rubio-Tapia A, Hill ID, Kelly CP, et al. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol 2013; 108:656.
  5. Rostom A, Dube C, Cranney A, et al. Celiac disease. Summary, evidence report/technology assessment No 104 (Prepared by the University of Ottawa Evidence-based Practice Center, under Contract, No. 290-02-0021), AHRQ publication No 04-E)29-1, Agency for Healthcare Research and Quality, Rockville, MD 2004.
  6. Henry J. Binder. Trastornos de la absorción. Harrison. Principios de Medicina Interna. Volumen 2. 19º Edición. 1933:1946
  7. S. Navarro Colás. Diarrea y malabsorción. Farreras Rozman. Medicina Interna. Volumen 1. 12º edición. 157:161
Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Increase in abdominal size


    Weight loss over the last 4-8 weeks


    Diarrhoea


    Belching


    Greasy diarrhoea

Symptoms to watch out for

Diarrhoea or discomfort for longer than 2 weeks
Vomiting
White, gaseous, voluminous and foul-smelling stools
Areas of skin filled with fluid accompanied by intense itching in elbows, knees, thighs, face, neck, torso and, occasionally, inside the mouth
If it is accompanied by seizures

Self-care

Gluten-free diet.
Avoid dairy products such as milk and cheese.
Consume vitamin supplements to compensate for the nutrients not obtained through food.