Depersonalisation disorder - Derealisation

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Depersonalisation is referred to a sensation of isolation or separation from oneself and one's own body, while derealisation is referred to a sensation of unreality or lack of connection with the surrounding world. Even though many people can have this one-time experience, if experienced repeatedly, or if it doesn't fully disappear, it can generate significant malaise, and it would be considered an established disorder.

The exact causes are still unknown, but it is believed that they may be related to biological, psychological and environmental factors.

Symptoms include depersonalisation and derealisation sensations, anxiety, nausea, confusion, depression and other emotional symptomatology.

To perform an accurate diagnosis, a professional in mental health will perform an in-depth clinical evaluation in which additional tests can be used such as a blood culture or brain imaging.

Treatment for depersonalisation-derealisation disorder can be based off of antidepressants and anxiolytics, as well as psychological therapy.

Bibliographic references
  1. Asociación Americana de Psiquiatría. Manual diagnóstico y estadístico de los trastornos mentales, quinta edición, revisión de texto (DSM-5-TR), Washington, DC 2022.
  2. Simeon D, Knutelska M. El papel del apego temeroso en el trastorno de despersonalización. Revista Europea de Trauma y Disociación 2022; 6.
  3. Hunter EC, Sierra M, David AS. La epidemiología de la despersonalización y la desrealización. Una revisión sistemática. Soc. Psiquiatría Epidemiol 2004; 39:9.
  4. Simeon D, Knutelska M, Nelson D, Guralnik O. Sentirse irreal: una actualización del trastorno de despersonalización de 117 casos. J Clin Psiquiatría 2003; 64:990.
  5. Baker D, Hunter E, Lawrence E, et al. Trastorno de despersonalización: características clínicas de 204 casos. Br J Psiquiatría 2003; 182:428.
 
 
Author
Dr. Abel Andrés Orelogio
Copyright
© TeckelMedical 2026

Symptoms

    Sensation of separation from the body


    Feeling of unreality of own body


    Sensation of separation of the body


    Difficulty experiencing feelings


    State of anxiety

Self-care

Maintain a balanced diet: increase fruit, vegetable, and white meat consumption and reduce the intake of fatty meals and fritters.
Engage in regular physical activity, adapted to age and physical condition, at least 3 times a week.
Often take part in activities that help reduce anxiety levels (yoga, tai chi, meditation).
Check with your general practitioner for psychotherapy and treatments.