Diabetes complications in pregnancy - Pregestational diabetes

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Diabetes known prior to the current pregnancy; it may be type 1 diabetes, type 2 diabetes or carbohydrate intolerance. These are characterised by the body's difficulty in regulating blood glucose levels adequately. Risk factors include obesity, family history of diabetes, polycystic ovary syndrome, among others.

Symptoms may include thirst, fatigue, blurred vision and increased risk of infections.

Pre-pregnancy diagnosis includes fasting blood glucose and other more specific tests. Prenatal monitoring is essential to reduce the risk of complications such as congenital malformations, foetal macrosomia, neonatal hypoglycaemia and pre-eclampsia.

Management involves controlling blood glucose levels through diet, exercise and, in some cases, medication. It is essential to follow a personalised care plan and medical follow-up.

Bibliographic references
  1. Chaturvedi N, Stephenson JM, Fuller JH. The relationship between pregnancy and long term maternal complications in the EURODIAB IDDM Complications study. Diabet Med. 1995;12:494-9.
  2. Shub A, Lappas M. Pregestational diabetes in pregnancy: Complications, management, surveillance, and mechanisms of disease-A review. Prenat Diagn. 2020 Aug;40(9):1092-1098. doi: 10.1002/pd.5718. Epub 2020 May 23. PMID: 32333803.
  3. Cleary EM, Thung SF, Buschur EO. Pregestational Diabetes Mellitus. 2021 Jul 26. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 34370429.
  4. Ali DS, Davern R, Rutter E, Coveney C, Devine H, Walsh JM, Higgins M, Hatunic M. Pre-Gestational Diabetes and Pregnancy Outcomes. Diabetes Ther. 2020 Dec;11(12):2873-2885. doi: 10.1007/s13300-020-00932-9. Epub 2020 Oct 3. PMID: 33010001; PMCID: PMC7644712.
Author
Dra. Maria Eugenia Rodriguez
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© TeckelMedical 2026

Symptoms

    Frequent urination


    Urinate a lot at night


    Thirst


    Passing large amounts of urine


    Feeling of hunger

Symptoms to watch out for

Dark or cola-coloured urine
If it is accompanied by seizures
A feeling of shortness of breath
Vomiting
Acute belly pain
Blurry vision

Self-care

Maintain a balanced diet: increase fruit, vegetable, and white meat consumption and reduce the intake of fatty meals and fritters.
Engage in regular physical activity, adapted to age and physical condition, at least 3 times a week.
Reduce tobacco consumption.
Wear comfortable, non-constricting footwear.
Lose weight if you are overweight or obese.
Check with your general practitioner about the prescription for medication to control blood glucose and insulin levels.