Drug-induced toxicoderma encompasses skin diseases that can affect the skin, mucous membranes, hair, nails, sweat glands, etc.
Any medication can cause it. The most frequent are some antibiotics, anti-epileptics and non-steroidal analgesics/anti-inflammatory drugs.
It manifests itself in a variety of ways, causing reddish patches that can coalesce to form large red areas, welts, scaling and/or itching of the skin.
Diagnosis is made on the basis of a complete medical history and physical examination.
The first thing to do to treat toxicoderma is to withdraw all questionable drugs. If the reaction produced by the drug is mild, the treatment used is symptomatic, including taking antihistamines and in some cases corticosteroids, topically or orally. If the reaction is severe, hospital admission to the intensive care unit or burns unit, fluid replacement and use of antimicrobials are necessary.
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