Gastric and/or duodenal ulcer

Low urgency
Common-

This is a lesion on the wall that lines the digestive tract, also known as the mucosa.

Predisposing/causing factors include infection by the Helicobacter pylori bacterium, smoking and the use of anti-inflammatory drugs.

It can sometimes be asymptomatic, but the most common symptoms are pain or discomfort in the middle and upper abdomen and heartburn.

The severity may increase with perforation or bleeding.

It is diagnosed by taking a clinical history and carrying out specific tests such as endoscopy and biopsy of the ulcer.

It is treated with medication to eliminate the Helicobacter pylori bacteria (if present) and to reduce stomach acid levels. Drinking limited amounts of coffee and not smoking or drinking alcohol is recommended.

Bibliographic references
  1. Nimish B Vakil. Epidemiology and etiology of peptic ulcer disease. UpToDate, Abril 2014
  2. Nimish B Vakil. Peptic ulcer disease: Clinical manifestations and diagnosis. UpToDate, Junio 2015
  3. Nimish B Vakil. Peptic ulcer disease: Management. UpToDate, Julio 2015
  4. John Del Valle. Úlcera péptica y trastornos relacionados. Harrison. Principios de Medicina Interna, 19e. Capítulo 348.
  5. J. P. Gisbert. Enfermedades del estómago y del duodeno. Farreras Rozman. Medicina Interna, ed 18. Capítulo 15
Author
Dr. Patricia Sánchez
Copyright
© TeckelMedical 2026

Symptoms

    Pain in the pit of the stomach


    Heartburn in pit of the stomach


    Abdominal pain between 00:00h and 3 a.m.


    Vomit blood


    Intermittent intense abdominal pain

Symptoms to watch out for

Abdominal pain that increases rapidly
Fever (temperature higher than 38 ºC)
Vomit with blood
Dark/black stools
History of immunodeficiency (HIV, diabetes mellitus, oncological disorders, long-term corticosteroid consumption).

Self-care

Reduce tobacco consumption.
Reduce alcohol consumption.
Eat small meals every day, rather than 2 or 3 large meals.
Avoid taking over-the-counter medications like non-steroidal anti-inflammatories.
Take an antacid 30 to 60 minutes before breakfast.