Heatstroke

High urgency
-Moderately severe

It occurs when the body loses its ability to regulate body temperature, exceeding 40°C on a sustained basis.

The exact cause is unknown, although a genetic predisposition is suggested. Factors have been described that:

a) Increase heat production (exercise, fever, drugs, thyroid disorders).
b) Decrease heat loss (high ambient heat and humidity, dehydration, drugs, less sweating).
c) Cause dysfunction of body regulation (disabled people).

Symptoms accompanying sustained high fever: flushing, sweat/dry skin, tachycardia, dizziness, headache, delirium, confusion and seizures. Severe cases can lead to the person's death.

Diagnosis is clinical by questioning and a physical examination. Blood tests and imaging tests are performed in order to rule out an infection.

The aim of treatment is to cool down the body (cool place, without clothes, compresses or towels soaked in cold water, etc.). It is advisable to avoid prolonged exposure to the sun, avoid exercise during the hottest hours of the day and to hydrate properly.

Bibliographic references
  1. C Crawford Mechem. Severe nonexertional hyperthermia (classic heat stroke) in adults. UpToDate. Jun 10, 2015.
  2. Lipman GS, Eifling KP, Ellis MA, et al. Wilderness Medical Society practice guidelines for the prevention and treatment of heat-related illness. Wilderness Environ Med 2013; 24:351.
  3. Druyan A, Janovich R, Heled Y. Misdiagnosis of exertional heat stroke and improper medical treatment. Mil Med 2011; 176:1278.
  4. Francis G O'Connor, Douglas J Casa. Exertional heat illness in adolescents and adults: Epidemiology, thermoregulation, risk factors, and diagnosis. UpToDate. Aug 31, 2015.
  5. Flores-Valderas J, Pérez-romero T, Palomo de los Reyes, MJ. Urgencias pòr calor. Manual de protocolos y actuación en urgencias. Hospital Virgen de la Salud, Complejo Hospitalario de Toledo. Tercera edición. 2010: 1393-1397.
Author
Dr. Sara Vitoria
Copyright
© TeckelMedical 2026

Symptoms

    High fever of 40ºC or above


    Dry skin


    Temperature > 41ºC / 105.8ºF


    Widespread muscle aches


    Low level of consciousness

Pre-hospital care recommendations

Consume over-the-counter pain relievers or anti-inflammatories.
Apply cold compresses 3 times a day for 20 minutes to reduce the symptoms.
Maintain hydration of 2 litres per day.
Relative rest, rest until symptoms subside.