It is a condition caused by a narrowing of the pylorus, the opening that contains the digestive tract that connects the stomach to the first part of the small intestine, or duodenum.
It mainly affects breastfeeding babies between 15 days and 2 months of age, and the causes are not known.
Vomiting is the first symptom in most babies. Other symptoms may appear a few weeks after birth and may include abdominal pain, belching, constant hunger, dehydration, inability to gain or lose weight, and a wave-like movement of the abdomen shortly after eating and just before vomiting.
The diagnosis is made by clinical history and physical examination, confirmed by abdominal ultrasound.
This condition is treated surgically.
- Anthony P Olivé, MD, Erin E Endom, MD. Infantile hypertrophic pyloric stenosis. Uptodate. Oct 19, 2016.
- Eberly MD, Eide MB, Thompson JL, Nylund CM. Azithromycin in early infancy and pyloric stenosis. Pediatrics 2015; 135:483.
- Krogh C, Fischer TK, Skotte L, et al. Familial aggregation and heritability of pyloric stenosis. JAMA 2010; 303:2393.
- Sommerfield T, Chalmers J, Youngson G, et al. The changing epidemiology of infantile hypertrophic pyloric stenosis in Scotland. Arch Dis Child 2008; 93:1007.
- Svenningsson A, Svensson T, Akre O, Nordenskjöld A. Maternal and pregnancy characteristics and risk of infantile hypertrophic pyloric stenosis. J Pediatr Surg 2014; 49:1226.

