Opiate poisoning

Medium urgency
-Moderately severe

Condition caused by the use of drugs derived from opium (morphine, oxycodone and synthetic opioid narcotics) or by consuming heroin.

The overdose may be accidental or intentional.

Symptoms include altered mental state, respiratory depression, low blood pressure and weak pulse.

The diagnosis is made with the medical history, physical examination and additional tests such as a CBC, tox screen, chest X-ray, electrocardiogram and CT-scan of the brain (if seizures).

Supportive and symptomatic treatment, together with an antidote called naloxone, will be administered as soon as possible, even in an outpatient setting.

Bibliographic references
  1. Andrew Stolbach, MD, Robert S Hoffman, MD. Acute opioid intoxication in adults. UpToDate. Jan 25, 2016.
  2. QuickStats: Number of Deaths From Poisoning,* Drug Poisoning,† and Drug Poisoning Involving Opioid Analgesics§ — United States, 1999–2010 www.cdc.gov/mmwr/preview/mmwrhtml/mm6212a7.htm?s_cid=mm6212a7_e (Accessed on April 08, 2013).
  3. Dart RC, Surratt HL, Cicero TJ, et al. Trends in opioid analgesic abuse and mortality in the United States. N Engl J Med 2015; 372:241.
  4. Binswanger IA, Blatchford PJ, Mueller SR, Stern MF. Mortality after prison release: opioid overdose and other causes of death, risk factors, and time trends from 1999 to 2009. Ann Intern Med 2013; 159:592.
  5. Spinner HL, Lonardo NW, Mulamalla R, Stehlik J. Ventricular tachycardia associated with high-dose chronic loperamide use. Pharmacotherapy 2015; 35:234.
  6. Indalecio Morán, Jaume Baldirà, Luís Marruecos, Santiago Nogué. Intoxicación por opiáceos y opióides. Intoxicación clínica. Capítulo 40. Páginas 483-497. Grupo Difusión.
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Symptoms

    Very small pupils


    Diminished level of consciousness


    Unable to pass urine


    Slow heart rate - bradycardia


    Coma

Pre-hospital care recommendations

Call medical assistance for instructions.
Do not leave the person suffering from the disease alone.