Inflammation of the sac-like layer that surrounds the heart to protect it.
It has many causes: infectious, neoplastic, autoimmune, renal insufficiency, hypothyroidism, etc.
It manifests itself as a sharp pain in the chest that can radiate to the neck, shoulders, back or abdomen. It gets worse when you lie down, take a deep breath, cough or swallow. Typically, it improves with sitting down and bending forward.
Diagnosis is based on clinical history, physical examination, electrocardiogram and may require imaging (chest x-ray, echocardiogram).
A patient with uncomplicated acute pericarditis can be treated on an outpatient basis. However, high-risk patients (high fever, significant pericardial effusion, heart failure and failure to respond to anti-inflammatory therapy) should be admitted to hospital for investigation. If a viral cause is suspected, rest and anti-inflammatory treatment will suffice. If a bacterial cause is suspected, antibiotic treatment and occasional drainage will be needed. In other situations, treatment will depend on the underlying condition.
- Imazio M. Clinical presentation and diagnostic evaluation of acute pericarditis. UpToDate. Feb 2016
- Spodick DH. Acute cardiac tamponade. N Engl J Med 2003; 349:684.
- Troughton RW. Pericarditis. Lancet 2004; 363:717.
- Sagristá Sauleda J. Guías de práctica clínica de la Sociedad Española de Cardiología en patología pericárdica. Rev Esp Cardiol 2000; 53: 394-412.
- Adler Y, et al. Colchicine treatment for recurrent pericarditis: a decade of experience. Circulation 1998; 97: 2183-5.

