Rocky Mountain spotted fever - Rickettsiosis

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It is an infectious disease caused by rickettsiae and transmitted by ticks. It is most common in spring and summer in wooded areas of the United States, Canada and Central America. It frequently affects children and adolescents who are active outdoors in wooded areas.

It is caused by the bacterium Rickettsia rickettsii, which lives inside the cells of other organisms. It is transmitted by the bite or blood of forest-dwelling ticks or animals such as dogs. 

Symptoms include severe headache, fever, muscle aches, nausea, vomiting and a skin rash. The rash usually affects wrists and ankles initially, spreading to palms, soles and the rest of the body quickly. In more severe cases, it can cause agitation, abdominal pain, respiratory failure, low blood pressure, coma and even death of the infected person.

Diagnosis is made by clinical examination, physical examination, blood tests and biopsy of the skin rash.

It is advisable to visit your GP in mild cases to confirm the diagnosis and start treatment. If you develop: low blood pressure, extensive skin lesions or altered level of consciousness, seek prompt medical attention at the nearest hospital for early medical evaluation.

Treatment is antibiotic; it should be early and maintained for 7 days. Doxacycline is the most commonly used antibiotic.

Bibliographic references
  1. Centers for Disease Control and Prevention. Rocky Mountain Spotted Fever. http://www.cdc.gov/rmsf/stats/#geography (Accessed on April 27, 2016).
  2. Traeger MS, Regan JJ, Humpherys D, et al. Rocky mountain spotted fever characterization and comparison to similar illnesses in a highly endemic area-Arizona, 2002-2011. Clin Infect Dis 2015; 60:1650.
  3. Thorner AR, Walker DH, Petri WA Jr. Rocky mountain spotted fever. Clin Infect Dis 1998; 27:1353.
  4. Demma LJ, Traeger MS, Nicholson WL, et al. Rocky Mountain spotted fever from an unexpected tick vector in Arizona. N Engl J Med 2005; 353:587.
  5. Centers for Disease Control and Prevention. Rocky Mountain Spotted Fever, Statistics and Epidemiology. http://www.cdc.gov/rmsf/stats/ (Accessed on September 12, 2017).
  6. David H. Walker, J. Stephen Dumler, Thomas Marrie. Enfermedades causadas por Rickettsias, Micoplasmas y Clamidias. Sección 10, capítulo 211. Harrison. Principios de Medicina Interna. Volumen 2. 19º Edición. 1154:1162.

 

 

Author
Dr. Oscar Garcia-Esquirol
Copyright
© TeckelMedical 2026

Symptoms

    Black mark at site of the bite


    Skin rash


    Rash in wrists and ankles towards palms of hands and soles of feet


    Nausea


    Localised abdominal pain

Pre-hospital care recommendations

Consume over-the-counter pain relievers or anti-inflammatories.