It is a life-threatening condition associated with increased serotonin activity in the central nervous system.
This syndrome is due to a sharp increase in serotonin in the brain. It is seen with the use of therapeutic drugs, inadvertent drug interactions and intentional overdose.
Symptoms include tachycardia and hypertension, hyperthermia (fever), involuntary jerky movements, tremor, dry mouth, sweating.
Diagnosis is made only by classical clinical signs in the context of taking the above-mentioned drugs. No laboratory test confirms the diagnosis.
Treatment varies according to the severity of the disease and includes cessation of medication, normalisation of vital signs and sedation with benzodiazepines. In severe cases, drugs that counteract the effects of serotonin will be administered.
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