It is the inflammation of the venous system, which can degenerate into deep vein thrombosis and/or pulmonary thromboembolism.
It is caused by diseases (cancer, congenital cardiopathies, nephrotic syndrome), trauma or intravenous catheters.
In many cases, it is not associated to symptoms. When it does manifest as deep vein thrombosis that goes along with swelling, reddening and pain in the extremity. If it starts as a pulmonary thromboembolism, it may develop into respiratory failure, collapse of blood circulation and even death.
Diagnosis is reached through clinical questioning, physical exploration and a Doppler colour ultrasound. Other complementary tests less common are: phlebography, CT-scan or MRI.
The treatment must be personalised, being anticoagulants the elective treatment.
- Kenet G, Nowak-Gôttl U. Venous thromboembolism in neonates and children . Best Practice&R esearch Clinical Haematology2012; 25: 333-344.
- Chan AK, deVeber G, Monagle P, Brooker LA, Massicotte PM.Venous thrombosis in children. J Thromb Haemost. 2003;1(7):1443-1455
- Setty BA, O’Brien SH, Kerlin BA. Pediatric venous thromboembolism in the United States: A tertiary care complication of chronic diseases. Pediatr Blood Cancer. 2012;59(2):258-264.
- Andrew M, David M, Adams M et al. Venous thromboembolic complications (VTE) in children: first analyses of the CanadianRegistry of VTE. Blood.1994;83(5):1251-1257.
- Van Ommen CH, Heijboer H, Buller HR, Hirasing RA,Heijmans HS, Peters M. Venous thromboembolism in childhood:a prospective two-year registry in The Netherlands. J Pediatr. 2001;139(5):676-681.
- Wright JM, Watts RG. Venous thromboembolism in pediatric patients: epidemiologic data from a pediatric tertiary care center in Alabama. J Pediatr Hematol Oncol. 2011;33(4):261-264.

